Ovulation induction
What is Ovulation induction?
couples who are unable to have children, hormone treatment can increase the chances of pregnancy. Although hormonal causes can be present in both men and women.Hormonal treatment in women aims to promote egg maturation and trigger ovulation. The success rates for each treatment cycle greatly depends on the age of the women ,antral follicular count and the extent of the underlying hormone disorder, ranging between 10 and 20%. In most cases, it therefore requires few cycles to achieve pregnanacy
How does hormone treatment work?
1.Cycle diagnostics - a. FSH b.LH c Serum estradiol D TSH e serum prolactin In addition the doctor uses ultrasound to monitor the follicular growth in the ovaries and to check whether and when ovulation occurs. This information is important to determine whether hormone treatment is necessary and which hormone preparations are most suitable for the treatment.
2.Treatment-Treatment usually starts from the 3rd to the 5th day of the menstrual cycle. a.Clomiphene citrate b. Letrozole c.FSH d.HMG e.rFSH
3.Ovulation monitoring-Serial ultrasound (follicular monitoring) is done from the 8th day of the cycle to see the size of follicles. Once follicle size reaches 18mmto 20mm ovulation is triggered by injection HCG at home you can also check ovulation by using LH ovulation testing kits. Timed intercourse or IUI can be performed as per trigger
When is hormone treatment useful?
Hormonal treatment is particularly suitable for women with ovulatory dysfunction. In most cases, the cause is a disturbance of the balance between the male hormone (androgen) and female hormone (oestrogen) (hyperandrogenism). In affected women, the follicles remain about 6-8 mm and ovulation does not occur.
In some women, increased numbers of egg follicles are found on the ovaries in an ultrasound scan. This disorder is referred to as polycystic ovary syndrome (PCOS). In these cases too, hormone therapy can be used to achieve maturation and subsequent ovulation.
There are also other hormonal causes of impaired follicle maturation.1. Hyperprolactinemia 2. hypothyroidism
Side effects and risk?
Hot flushes
Headaches
Depressive moods
Hyperstimulation
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